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Anti-Mouse F4/80 Antigen PE 抗小鼠F4/80抗原PE抗體

  • 更新時(shí)間：  2023-07-24
  • 產(chǎn)品型號(hào)：  eBiosience12-4801-82
  • 簡單描述
  • Host
    Rat
    Isotype
    IgG2a, kappa
    Reactivity
    Mouse
    Conjugate
    PE
    Laser
    Blue Laser, Green Laser, Yellow-Green Laser
    Emit
    575 nm
    Excite
    488 - 561 nm
    Reported Applications
    Flow Cytometric Analysis
詳細(xì)介紹

Also known as: Pan Macrophage Marker

Clone: BM8

Description: The BM8 monoclonal antibody reacts with mouse F4/80 antigen, an approximay 125 kDa transmembrane protein. The F4/80 antigen is expressed by a majority of mature macrophages and is the best marker for this population of cells. However, other cell types such as Langerhans cells and liver Kupffer cells have been reported to express this antigen. Expression of F4/80 commences during early myeloid development and is upregulated on all BM cells stimulated in vitro with M-CSF. It has been shown that some cytokines downregulate the expression of F4/80 resulting in lack of F4/80 antigen on a subpopulation of macrophages, especially in the lymphoid microenvironment in vivo

Host Rat
Isotype IgG2a, kappa
Reactivity Mouse
Conjugate PE
Laser Blue Laser, Green Laser, Yellow-Green Laser
Emit 575 nm
Excite 488 - 561 nm
Reported Applications Flow Cytometric Analysis

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